Do H, Kwon S, Baek S, Madukoma CS, Smiley MK, Dietrich LE, Shrout J and Bohn PW (2021)
Redox cycling-based detection of phenazine metabolites secreted from Pseudomonas aeruginosa in nanopore electrode arrays
Analyst, DOI: 10.1039/D0AN02022B
Wang B, Lin YC, Jo J, Price-Whelan A, McDonald ST, Brown LM, Dietrich LEP (2020) 
Pseudomonas aeruginosa PA14 biofilms produce R-bodies, extendable protein polymers with roles in host colonization and virulence. 
bioRxiv 2020.10.26.356394; doi: https://doi.org/10.1101/2020.10.26.356394
Shi L, Liu X, Shi L, Stinson HT, Rowlette J, Kahl LJ, Evans CR, Zheng C, Dietrich LEP, & Min W (2020)
Mid-infrared metabolic imaging with vibrational probes. 
Nature Methods, 17(8), 844–851
Evans CR, Kempes CP, Price-Whelan A, Dietrich LEP (2020)
Metabolic Heterogeneity and Cross-Feeding in Bacterial Multicellular Systems.
Trends in Microbiology
Cornell WC, Zhang Y, Bendebury A, Hartel AJW, Shepard KL, & Dietrich, LEP (2020)
Phenazine oxidation by a distal electrode modulates biofilm morphogenesis.
Biofilm, 100025.​​​​​​
Kahl, LJ, Price-Whelan, A, & Dietrich, LEP (2020).
Light-mediated decreases in cyclic di-GMP levels inhibit structure formation in Pseudomonas aeruginosa biofilms. 
Journal of Bacteriology 202 (14)
Hardie KR, Mathee K, Schweizer HP, Dietrich LE, Welch M, de Kievit T, Nguyen D, Kivisaar M, Dandekar AA, McDougald D, & Winstanley C (2020)
Pseudomonas 2019 meeting report. 
Journal of Medical Microbiology. https://doi.org/10.1099/jmm.0.001208
Luu GT, Condren AR, Kahl LJ, Dietrich LEP, Sanchez LM (2020)
Evaluation of data analysis platforms and compatibility with MALDI-TOF imaging mass spectrometry data sets
Journal of the American Society for Mass Spectrometry

Jo J, Price-Whelan A, Cornell WC, Dietrich LEP (2020)
Interdependency of respiratory metabolism and phenazine-associated physiology in Pseudomonas aeruginosa PA14.
Journal of Bacteriology 202 (4)
Dayton H, Smiley MK, Forouhar F, Harrison JJ, Price-Whelan A, Dietrich, LEP (2020) 
Sensory Domains That Control Cyclic di-GMP-Modulating Proteins: A Critical Frontier in Bacterial Signal Transduction. 
In S.-H. Chou, N. Guiliani, V. T. Lee, & U. Römling (Eds.), Microbial Cyclic Di-Nucleotide Signaling (pp. 137–158). Springer International Publishing.
Condren AR, Kahl LJ, Boelter G, Kritikos G, Banzhaf M, Dietrich LEP, Sanchez LM (2020)
Biofilm inhibitor taurolithocholic acid alters colony morphology, specialized metabolism, and virulence of Pseudomonas aeruginosa.
ACS Infectious Diseases​​​​​​​
Schiessl KT, Hu F, Jo J, Nazia SZ, Wang B, Price-Whelan A, Min W, and Dietrich LEP (2019)
Phenazine Production Promotes Antibiotic Tolerance and Metabolic Heterogeneity in Pseudomonas aeruginosa biofilms
Nature Communications 10 (1): 762.
Lin YC, Cornell WC, Price-Whelan A, Dietrich LEP (2018)
The Pseudomonas aeruginosa complement of lactate dehydrogenases enables use of D- and L-lactate and metabolic crossfeeding
MBio (9) doi:10.1128/mBio.00961-18
Cornell WC, Morgan CJ, Koyama L, Sakhtah H, Mansfield JH, Dietrich LEP (2018)
Paraffin embedding and thin sectioning of microbial colony biofilms for microscopic analysis
Journal of Visualized Experiments (133)
Sporer A, Beierschmitt A, Bendebury A, Zink K, Price-Whelan ABuzzeo MC, Sanchez L, Dietrich LEP (2018)
The phenazine utilizing monooxygenase PumA affects biofilm physiology in Pseudomonas aeruginosa
Microbiology 164(5), 790–800
Lin YC, Sekedat MD, Cornell WC, Silva GM, Okegbe C, Price-Whelan A, Vogel C and Dietrich LEP (2018)
Phenazines regulate Nap-dependent denitrification in Pseudomonas aeruginosa biofilms
Journal of Bacteriology 200(9), e00031-18
Jo J, Cortez KL, Cornell WC, Price-Whelan A, Dietrich LE (2017)
An orphan cbb3-type cytochrome oxidase subunit supports Pseudomonas aeruginosa biofilm growth and virulence
eLife 6:e30205
Fong JCN, Rogers A, Michael AK, Parsley NC, Cornell WC, Lin YC, Singh PK, Hartmann R, Drescher K, Vinogradov E, Dietrich LEP, Partch CL, Yildiz FH (2017)
Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
eLife 6:e26163
Sporer A, Kahl L, Price-Whelan A, Dietrich LEP (2017)
Redox-based regulation of bacterial development and behavior
Annual Review of Biochemistry 86:777-797
Okegbe C, Fields BL, Cole SJ, Beierschmitt C, Morgan CJ, Price-Whelan A, Stewart RC, Lee VT, Dietrich LEP (2017)
Electron-shuttling antibiotics structure bacterial communities by modulating cellular levels of c-di-GMP
Proceedings of the National Academy of Sciences of the United States of America 114(26)
Arnaouteli S, Ferreira AS, Schor M, Morris RJ, Bromley KM, Jo J, Cortez KL, Sukhodub T, Prescott AR, Dietrich LEP, MacPhee CE, Stanley-Wall NR (2017)
Bifunctionality of a biofilm matrix protein controlled by redox state
Proceedings of the National Academy of Sciences of the United States of America 114(30)
Maderbocus R, Fields BL, Hamilton K, Luo S, Tran T, Dietrich LE, Tong L (2017)
Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer
Nature Communications 8: 160
Choi PH, Jo J, Lin YC, Lin MH, Chou CY, Dietrich LE, Tong L (2016)
A distinct holoenzyme organization for two-subunit pyruvate carboxylase
Nature Communications 7:12713
Sakhtah H, Koyama L, Zhang Y, Morales DK, Fields BL, Price-Whelan A, Hogan DA, Shepard K, Dietrich LEP (2016)
The Pseudomonas aeruginosa efflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development
Proceedings of the National Academy of Sciences of the United States of America 113(25), E3538–E3547
Bellin DL, Sakhtah H, Zhang Y, Price-Whelan A, Dietrich LEP*, Shepard KL* (2016)
Electrochemical camera chip for simultaneous Imaging of multiple metabolites in biofilms
Nature Communications 7:10535
* corresponding authors
Madsen JS, Lin YC, Squyres GR, Price-Whelan A, de Santiago Torio A, Song A, Cornell WC, Sørensen SJ, Xavier JB, Dietrich LEP (2015)
Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa PA14 biofilm models. Appl Environ Microbiol. 81(24), 8414-26
highlighted in AEM Spotlight
Holscher, T., Bartels, B., Lin, Y. C., Gallegos-Monterrosa, R., Price-Whelan, A., Kolter, R., Dietrich LEP, Kovacs, A. T. (2015). Motility, chemotaxis and aerotaxis contribute to competitiveness during bacterial pellicle biofilm development. Journal of Molecular Biology. doi: 10.1016/j.jmb.2015.06.014
recommended in Faculty of 1000
Tran TH, Hsiao Y-S, Jo J, Chou, C-Y, Dietrich LEP, Walz T, & Tong L (2015)
Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.
Nature 518(7537), 120–124
Chen AI, Dolben EF, Okegbe C, Harty, Golub Y, Thao S, Ha DG, Willger SD, O'Toole GA, Harwood CS, LEP Dietrich, DA Hogan (2014)
Candida albicans Ethanol Stimulates Pseudomonas aeruginosa WspR-Controlled Biofilm Formation as Part of a Cyclic Relationship Involving Phenazines.
PLoS Pathogens 10(10):e1004480
Jo J, Price-Whelan A, Dietrich LEP (2014)
An Aerobic Exercise: Defining the Roles of Pseudomonas aeruginosa Terminal Oxidases.
Journal of Bacteriology 196(24):4203-4205
Okegbe C, Price-Whelan A, Dietrich LEP (2014)
Redox-driven regulation of microbial community morphogenesis.
Current Opinion in Microbiology 18: 39–45
Bellin DL, Sakhtah H, Rosenstein JK, Levine PM, Thimot J, Emmett K, Dietrich LEP*, Shepard KL* (2014)
Integrated circuit-based electrochemical sensor for spatially resolved detection of redox-active metabolites in biofilms.
Nature Communications 5:3256
* corresponding authors
highlighted in Columbia University News, ASM Microbe , Xinhua News
Kempes C, Okegbe C, Mears-Clarke Z, Follows M, Dietrich LEP (2014)
Morphological optimization for access to dual oxidants in biofilms.
Proceedings of the National Academy of Sciences of the United States of America 111(1):208-13
highlighted in MIT news
Sakhtah H, Price-Whelan A, Dietrich LEP (2014)
Regulation of phenazine biosynthesis.
in Microbial Phenazines: Biosynthesis, Agriculture and Health (Springer)
van Ditmarsch D, Boyle KE, Sakhtah H, Oyler JE, Nadell CD, Deziel E, Dietrich LEP, Xavier JB (2013)
Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria.
Cell Reports 4(4): 697-708
highlighted in NY Times
Morales DK, Grahl N, Okegbe C, Dietrich LE, Jacobs NJ, Hogan DA. (2013)
Control of Candida albicans Metabolism and Biofilm Formation by Pseudomonas aeruginosa Phenazines.
MBio 4(1):e00526-12
Dietrich LEP*, Okegbe C, Price-Whelan A, Sakhtah H, Hunter RC, Newman DK (2013)
Bacterial community morphogenesis is intimately linked to the intracellular redox state
Journal of Bacteriology 195(7):1371-80
* corresponding author
Sheplock R, Recinos DA, Mackow N, Dietrich LE*, Chander M* (2013)
Species-specific residues calibrate SoxR sensitivity to redox-active molecules.
Molecular Microbiology 87(2):368-81
* corresponding authors
Recinos DA, Sekedat MD, Hernandez A, Cohen TS, Sakhtah H, Prince AS, Price-Whelan A, Dietrich LE (2012)
Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity.
Proceedings of the National Academy of Sciences of the United States of America 109(47):19420-5
recommended in Faculty of 1000
Murray TS, Okegbe C, Gao Y, Kazmierczak BI, Motterlini R, Dietrich LEP, Bruscia EM (2012)
The Carbon Monoxide Releasing Molecule CORM-2 Attenuates Pseudomonas aeruginosa Biofilm Formation.
PLoS ONE 7, e35499 (2012)
Okegbe C, Sakhtah H, Sekedat M, Price-Whelan A, Dietrich LEP (2012)
Redox Eustress: Roles for Redox-Active Metabolites in Bacterial Signaling and Behavior.
Antioxidants & Redox Signaling, 16(7):658-67
D'aes J, Hua GK, De Maeyer K, Pannecoucque J, Forrez I, Ongena M, Dietrich LE, Thomashow LS, Mavrodi D, Höfte M (2011)
Biological control of Rhizoctonia root rot on bean by phenazine and cyclic lipopeptide producing Pseudomonas CMR12a. Phytopathology 101(8):996-1004
Dietrich LE, Kiley PJ (2011)
A shared mechanism of SoxR activation by redox-cycling compounds
Molecular Microbiology 79 (5), 1119-1122
Ramos I*, Dietrich LE*, Price-Whelan A, Newman DK (2010)
Phenazines affect biofilm formation by Pseudomonas aeruginosa in similar ways at various scales.
Research in Microbiology  161:187-191
(* contributed equally)
Dietrich LE, Teal TK, Price-Whelan A, Newman DK (2008)
Redox-active antibiotics control gene expression and community behavior in divergent bacteria.
Science 321(5893):1203-6;
highlighted in C&E News
Gorodetsky A*, Dietrich LE*, Lee P, Newman DK, Barton JK (2008)
DNA Binding shifts the Redox Potential of the Transcription Factor SoxR.
Proceedings of the National Academy of Sciences of the United States of America 105: 3684-9
(* contributed equally)
Recommended in Faculty of 1000
Price-Whelan A, Dietrich LE, Newman DK (2007)
Pyocyanin alters redox homeostasis and carbon flux through central metabolic pathways in Pseudomonas aeruginosa PA14. Journal of Bacteriology 189: 6372-6381
Dietrich LE, Price-Whelan A, Petersen A, Whiteley M, Newman DK (2006)
The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa. Molecular Microbiology 61: 1308-1321
Recommended in Faculty of 1000
Dietrich LE, Tice MM, Newman DK (2006)
The co-evolution of life and Earth.
Current Biology 16: R395-400
Price-Whelan A, Dietrich LE, Newman DK (2006)
Rethinking 'secondary' metabolism: physiological roles for phenazine antibiotics.
Nature Chemical Biology 2: 71-78
Subramanian K*, Dietrich LE*, Hou H, LaGrassa TJ, Meiringer CT, Ungermann C (2006)
Palmitoylation determines the function of Vac8 at the yeast vacuole. 
Journal of Cell Science 119: 2477-2485 (* contributed equally)
Dietrich LE, Peplowska K, LaGrassa TJ, Hou H, Rohde J, Ungermann C (2005)
The SNARE Ykt6 is released from yeast vacuoles during an early stage of fusion.
EMBO Reports 6: 245-250
Hou H, Subramanian K, LaGrassa TJ, Markgraf D, Dietrich LE, Urban J, Decker N, Ungermann C (2005)
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8.
Proceedings of the National Academy of Sciences of the United States of America 102: 17366-17371
Dietrich LE, LaGrassa TJ, Rohde J, Cristodero M, Meiringer CT, Ungermann C (2005)
ATP-independent control of Vac8 palmitoylation by a SNARE subcomplex on yeast vacuoles.
The Journal of Biological Chemistry 280: 15348-15355
Dietrich LE, Ungermann C (2004) 
On the mechanism of protein palmitoylation.
EMBO Reports 5: 1053-1057
Rossi V, Banfield DK, Vacca M, Dietrich LE, Ungermann C, D'Esposito M, Galli T, Filippini F (2004)
Longins and their longin domains: regulated SNAREs and multifunctional SNARE regulators.
Trends in Biochemical Sciences 29: 682-688
Dietrich LE, Gurezka R, Veit M, Ungermann C (2004)
The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion.
The EMBO Journal 23: 45-53
Recommended in Faculty of 1000
Dietrich LE, Boeddinghaus C, LaGrassa TJ, Ungermann C (2003)
Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins.
Biochimica et Biophysica Acta 1641: 111-119
Veit M, Dietrich LE, Ungermann C (2003)
Biochemical characterization of the vacuolar palmitoyl acyltransferase.
FEBS letters 540: 101-105
Rohde J, Dietrich L, Langosch D, Ungermann C (2003)
The transmembrane domain of Vam3 affects the composition of cis- and trans-SNARE complexes to promote homotypic vacuole fusion.
The Journal of Biological Chemistry 278: 1656-1662
Veit M, Laage R, Dietrich L, Wang L, Ungermann C (2001)
Vac8p release from the SNARE complex and its palmitoylation are coupled and essential for vacuole fusion.
The EMBO Journal 20: 3145-3155
Dietrich L, Ehrlich LS, LaGrassa TJ, Ebbets-Reed D, Carter C (2001)
Structural consequences of cyclophilinA binding on maturational refolding in human immunodeficiency virus type 1 capsid protein. Journal of Virology 75: 4721-4733
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